As of mid-2026, the current (second-generation) Nanopub Registry tracks roughly 80,000 signed nanopublications, with the count growing continuously; the live total is shown on the registry's homepage. Different registry instances may report slightly different totals depending on which nanopublications they accept (for example, by trusted agents or by type), so a single number should be understood as a snapshot of one particular registry. In addition, the earlier first-generation nanopub-server network still preserves the historical, mostly unsigned nanopublications accumulated over the past decade — currently around 11 million. This legacy network no longer plays an active role in the current ecosystem but remains accessible as an archive.